Droplet-Generating Microfluidic Devices for Soluble Assays

ogy in the pharmaceutical industry (1). Over the past decade, there has been a logarithmic increase in the industry’s ability to screen large combinatorial libraries of compounds against target molecules (2). The technology to achieve this has come in the form of robotics, high-density microplates, small volume (microliter) liquid handling, and sophisticated detection schemes. Signifi cant effort has gone into the design of HTS workstations capable of screening tens of thousands of compounds in a 24-h period. However, these workstations come with a large price tag, ranging from several hundred thousand to millions of dollars.